Jack’s Corner is a nonprofit organization dedicated to improving the quality of life and finding a cure for children with SPG50 through the acceleration of gene therapy treatments, funding of research, and raising awareness of the disease. SPG50 is an ultra-rare neurodegenerative disease that affects children. The disease causes spasticity that starts in chldren's legs, slowly taking away their ability to walk. The spasticity then takes away their ability to use their hands, and ultimately, their mental capacity.