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The Isaac Foundation Love Laughter And Hope Providing support and advocacy for patients and families coping with rare diseases. Our Mission Statement Love Laughter and Hope The Isaac Foundations mission is to fund innovative research projects that aim to find a cure for MPS a rare debilitating and devastating disease. We provide support for families of individuals suffering from MPS and advocate on their behalf to ensure government funding for expensive lifesustaining treatments are covered by the health care system. Since 2007 we have provided over 1 million to research grants for projects around the world that seek to cure and improve current treatments for MPS diseases.