Defenders of Wildlife leads the pack when it comes to protecting wild animals and plants in their natural communities. #ActAgainstExtinction Defenders of Wildlife leads the pack when it comes to protecting wild animals and plants in their natural communities. Defenders of Wildlife is a national, non-profit membership organization dedicated to the protection of all native wild animals and plants in their natural communities. Our Conservation Vision: Defenders of Wildlife envisions a future where diverse wildlife populations in North America are secure and thriving, sustained by a network of healthy lands and waters.