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ANNOUNCING THE 3rd INTERNATIONAL TOPDOWN PROTEOMICS SYMPOSIUM August 2628 2025University of Hamburg Germany EducationCommunityInnovative Research Accelerating the comprehensive analysis of all human proteoforms Speeding developments in diagnostics therapeutics environment and energy The Human Proteoform Project An ambitious initiative to generate a definitive reference set of the proteoforms produced from the genome providing the bridge from genotype to phenotype Proteoform Thursday April 24 Philipp Kaulich presents Properties Origin and Reproducibility of Truncated Proteoforms in Recent TopDown Proteomic Studies Proteoform Thursday March 20 Jeff Agar presents Intact Mass Assay Enables Animal Studies of Covalent DrugTarget Binding and Determination of PKPD Parameters Proteoform Thursday December 12 Tarick ElBaba presents Isolation of Metabotropic Glutamate Receptors from Human Brain Uncovers Remodeling in Depression Proteoform Thursday October 17 Oliver Hale presents Enabling Molecular Pathology of Intact Proteoform Complexes in Tissue by Mass Spectrometry Proteoform Thursday September 26 Vendor Showcase presents the latest tech and apps Proteoform Thursday August 29 Novera Alam presents Internal fragment disambiguation and visualization methods improve the depth of topdown mass spectrometry analysis Proteoform Thursday July 25 Fabio Gomes presents Native TopDown Characterization of Proteoforms and their Complexoforms in Breast Cancer Cells TopDown Proteomics Workshop at ASMS2024 Native TopDown Initiative Publishes Results of Community Study Thank you to our Consortium Major Sponsors Thank you to our Consortium Supporters Discover Proteoforms Characterize Antibodies. Elucidate Native States. Image Tissues. Welcome to the TopDown Community A nonprofit organization with members from academic institutions corporations and government agencies.